Cystic fibrosis answers, with the sources.

Asha does not diagnose or prescribe. She explains the evidence, cites it, and tells you when to get care today.

The CF team is a phone call away, yet questions pile up between visits: a new cough, a lower appetite, a modulator side effect. Patients and the people who love them arrive here carrying those questions. Asha explains the evidence with its sources, and says plainly when the next step is a call to the team today.

Ask Asha: What CFTR modulators do Which signs are urgent

Five questions, no accountBuilt by two physiciansCited on every answer

Asha in your pocket

What patients and families ask

Modulators, exacerbations, CF-related diabetes, airway clearance.

Cystic fibrosis care has changed with CFTR modulators, and the daily work of airway clearance and nutrition continues alongside them. Between clinic visits the hard part is judging a change: a cough that lingers, or an appetite that drops. The questions below help sort what is routine from what needs the CF team today.

What CFTR modulators doWhat do CFTR modulators such as Trikafta do in cystic fibrosis, and who is eligible by mutation? What side effects and monitoring go with them?Ask this Exacerbation or a bad weekMy child with cystic fibrosis has a new cough and a lower appetite. What counts as a pulmonary exacerbation, and when do we call the CF team?Ask this CF-related diabetes and screeningHow is cystic fibrosis-related diabetes different from the usual types of diabetes, and how and when is it screened for?Ask this Airway clearance and a school dayWhat does the evidence say about airway clearance routines in cystic fibrosis, and how do families fit them into a school day?Ask this

Open Asha and ask your own

Do not wait for the next visit

Go to the emergency department, or call 911, if

coughing up blood, more than a few streaks, or any amount that keeps coming
sudden sharp chest pain, or sudden severe breathlessness
breathing that is fast or labored, blue or gray lips, or new confusion
severe belly pain with swelling, vomiting, or no stool passing
a fever with a worsening cough, when the CF team cannot see you today
dizziness, cramps, confusion or fainting after heavy sweating in the heat

Bleeding, a collapsed lung and a bowel blockage can worsen fast, so tell the emergency team about the cystic fibrosis and the CF center.

988 call or text, mental-health crisis 911 danger to life or limb

For the people around them

For the people around the patient

A newborn screen that comes back flagged lands on parents who have never heard the words. Partners of adults with cystic fibrosis learn the treatment routine, and when to step back from it.

After a flagged newborn screenOur newborn's screening test flagged cystic fibrosis. What happens next, what does a sweat test show, and what does it mean to be a carrier?Ask this Supporting a partner with CFMy partner has cystic fibrosis. How can I support daily treatments and airway clearance without taking them over, and which changes should worry me?Ask this

A thin teal key standing upright in a pool of translucent ivory liquid, its ring above the surface and its four pins to the right.

Know what is normal. Know what is urgent.

Tell Asha what is happening, in your own words. She answers from the evidence, shows where it comes from, and says plainly when the next step is a clinician today.

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How Asha answers

The evidence, its sources, and the line she will not cross.

Cited

Every answer shows its sources.

For cystic fibrosis, Asha reads the Orphanet rare-disease catalogue, the Human Phenotype Ontology, PubMed-indexed abstracts and the wider biomedical literature.

Plain

She says when it is serious.

Asha does not diagnose or prescribe. She explains the evidence, cites it, and tells you when to get care today. When a symptom cannot wait, she says so first, and she gives the number to call.

Private

Five questions, no account.

Ask without signing up. Your conversations are private and are never sold. For clinicians: each answer lists the sources it drew on, so the evidence can be checked directly.

Clinicians. Asha Clinical, for verified clinicians: NPI verification in under a minute. Verify and open clinician mode.

Patient organizations and clinics. Asha can be listed as a resource for your community, and the founders speak to families. Write to us through Support.

About Asha. Asha is built by DNAi Systems, founded by two physicians. Answers are grounded in a curated medical knowledge base and checked against safety rules before they reach you. Five questions, no account. Then the first month free with a card. Your conversations are private and are never sold. Privacy, safety, pricing.

Your Key to Wellbeing

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If you are in crisis, call or text 988. In immediate danger, call 911.